Singapore legislation

Regulation 18

of Health Products (Clinical Research Materials) Regulations 2016

Regulation 18

Production of and time for keeping of records

Amended byS 108/2021 wef 01/03/2021S 108/2021 wef 01/03/2021

Subregulation 1

A person who is required to keep any record under this Division must —

(a)

keep the records for the applicable period specified in paragraph (2) or (3); and

(b)

produce the records for inspection when required by the Authority at any reasonable time during the applicable period.

Subregulation 2

Amended byS 108/2021 wef 01/03/2021

For records relating to any manufacture, assembly and testing of clinical research material, the applicable period is as follows:

(a)

in the case of registered and unregistered investigational clinical research material and unregistered auxiliary clinical research material — 5 years after the completion or discontinuation of the last clinical trial in which the batch of that material was used;

(b)

in the case of registered auxiliary clinical research material, the longer of the following periods:

(i)

one year after the expiry date of the material;

(ii)

5 years after the date of such manufacture, assembly and testing;

(c)

in the case of traceability records relating to clinical research material that is a CTGT product — 30 years after the expiry date of the product or any other shorter period that the Authority allows in a particular case.

Subregulation 3

Amended byS 108/2021 wef 01/03/2021

For records relating to the receipt and supply of, or the putting to some other use, disposal or export, of clinical research material, the applicable period is as follows:

(a)

where the clinical research is not a regulated trial and —

(i)

the clinical research material is not a CTGT product — 2 years after the supply, putting to some other use, disposal or export, as the case may be; or

(ii)

the clinical research material is a CTGT product and —

(A)

the records do not relate to traceability — 2 years after the supply, putting to some other use, disposal or export, as the case may be; or

(B)

the records relate to traceability — 30 years after the expiry of the CTGT product, or any other shorter period that the Authority allows in a particular case;

(b)

where the clinical research is a regulated clinical trial, the period for which records of the trial must be kept under regulation 23(2)(c) of the Health Products (Clinical Trials) Regulations 2016 (G.N. No. S 331/2016) or regulation 23(2)(c) of the Medicines (Clinical Trials) Regulations 2016 (G.N. No. S 335/2016), as the case may be.